Research & Development Report

Cucumber Extract and Osteorathritis Relief

According to the CDC osteorarthritis (OA) affects more than 35 million U.S. adults.1 This degenerative joint disease occurs most frequently in hands, hips, and knees. The cartilage within a joint begins to break down and the underlying bone begins to change. These changes usually develop slowly and gradually get worse over time. OA can cause pain, stiffness, and swelling that may lead to reduced function. Current medical treatments for OA include anti-inflammatory drugs, synthetic forms of cortisone injections, and surgery.2 Because OA may lead to reduced quality of life the use of efficacious nutraceutical alternatives are growing in popularity.

In our research we found Q-Actin to be especially effective in the reduction of OA pain and inflammation.3 Q-Actin is a registered cucumber extract that has published double-blind clinical studies that demonstrate improvements in joint pain and function. Iminosugars is a class of bioactive carbohydrates isolated from cucumber and may play a role in ameliorating joint pain and improving function. A supplement containing only 20 mg of Q-Actin daily was shown to reduce inflammatory markers, including tumor necrosis factor alpha (TNF-alpha) and interleukin-6 which can drive degenerative changes in joints when elevated. 

Clinical trials have shown that Q-actin improves joint function and mobility better than a placebo and even outperforms the popular supplement, glucosamine-chondroitin in relieving knee discomfort. Q-actin is an effective supplement for promoting joint flexibility, strength and comfort, making everyday activities easier.

Plant Science continues its research and development in creating efficacious formulations for consumers. The R&D investment is an asset to nutraceutical companies that want to grow market share.

1
Osteoarthritis (QA). Centers for Disease Control and Prevention. (www.cdc.gov/arthritis/basics/osteoarthritis.htm).
2
Gene Bruno, “Cucumber Extract: A Novel Nutraceutical Treatment for Osteoarthritis,” Vitamin Retailer, April 2021.
3
Robert James Nash et al. “Standardized ido-BR1 Cucumber Extract Improved Parameters Linked to Moderate Osteoarthritis in a Placebo-controlled Study. Curr Rheumatol Rev. 2023 Jun 5; 19 (3): 345-351.
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