Research & Development Report

The Nutritional Combination Needed with Collagen for Efficacious Bone and Joint Health

Bone and joint nutritional support is needed earlier than most people realize. Joint issues begin in both men and women as early as 30-40 years of age. A flexibility study found that once men and women hit this age, flexibility drops significantly and unfortunately just keeps going down.1 

The need is increasing with the aging population for an efficacious supplement that supports bone and joint health through nutrition. Studies report the Collagen UC-II to be efficacious for the treatments of arthritis. A statistically significant improvement in knee joint function over a placebo was reported in a clinical study of  healthy individuals. The study also reported after 120 days of supplementation with UC-II collagen reported longer duration of strenuous exercise before transient knee joint pain was experienced. 

However, collagen alone is only part of the nutritional requirement for joint and bone health. Studies show cartilage, bone density and strength are improved through a combination of nutrients, including: Collagen, Vitamin D, Zinc, and calcium.3  The uniqueness of this combination is that the nutritional elements actually aid in the absorption and effectiveness of each of the nutrients. In effect, it is through this combination that nutritional support for bone and joint health is improved.

Plant Science continues to evaluate studies in the development of efficacious supplements. The investment in research is important to the ongoing development of custom formulations.

1
Hugo Baptista de Oliveira Medeiro, et al. “Age-related mobility loss is joint-specific: an analysis from 6,000 Flexitest results,” PMC (Mar 27, 2013) PMID 23529505.
2
Lugo, J.P., Saiyed, Z.M. & Lane, N.E. Efficacy and tolerability of an undenatured type II collagen supplement in modulating knee osteoarthritis symptoms: a multicenter randomized, double-blind, placebo-controlled study. Nutr J 15, 14 (2015).
3
NIH Health Sheet, “Vitamin D Fact Sheet for Health Professionals”; T.H. Chan, “The Nutrition Source,” Harvard School of Public Health, hsph.harvard.edu.; Negin Amin, et al, “Zinc supplements and bone health: The role of the RANKL-RANK axis as a therapeutic target,” Journal of Trace Elements in Medicine and Biology, Vol 57, January 2020; NIH Health Sheet, “Calcium Fact Sheet for Professionals.”
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